Page 21 - RPIA_27-1
P. 21
REAÇÕES ADVERSAS A MEIOS DE CONTRASTE IODADOS / ARTIGO DE REVISÃO
ação do imunoalergologista. A sua atuação deverá ter 9. Lasser EC, Kolb WP, Lang JH. Letter: Contrast media activation
como foco principal a confirmação de que se tratou de of serum complement system. Invest Radiol 1974;9:6.
10. Brockow K, Romano A, Aberer W, Bircher AJ, Barbaud A, Bo-
uma reação adversa (seja imunológica ou não) ao fárma-
nadonna P, et al. European Network of Drug Allergy and the
co, evitando a restrição excessiva do uso dos MCRI. Após EAACI interest group on drug hypersensitivity. Skin testing in
identificação do agente causal, é importante fazer a evic- patients with hypersensitivity reactions to iodinated contrast
ção do MCRI responsável, escolher um MCRI (LOCM) media – a European multicenter study. Allergy 2009;64: 234 -41.
11. Böhm I, Schild HH. A practical guide to diagnose lesser -known
alternativo mediante o resultado de testes cutâneos (TCP,
immediate and delayed contrast media -induced adverse cutaneous
TID, Epi) e administrar pré -medicação com corticoides reactions. Eur Radiol 2006;16:1570 -9.
e anti -histamínicos como profilaxia de uma eventual rea- 12. Katayama H, Yamaguchi K, Kozuka T, Takashima T, Seez P, Mat-
ção em doentes com reação prévia ou com outros fato- suura K. Adverse reactions to ionic and nonionic contrast media.
A report from the Japanese Committee on the Safety of Contrast
res de risco para o desenvolvimento de reações adversas.
Media. Radiology 1990;175:621 -8.
13. Schabelman E, Witting M. The relationship of radiocontrast, io-
Contacto: dine, and seafood allergies: a medical myth exposed. J Emerg Med
João Marcelino 2010;39:701 -7.
E-mail: JLAM_1987@sapo.pt 14. Stellato C, de Crescenzo G, Patella V, Mastronardi P, Mazzarella
B, Marone G. Human basophil/mast cell releasability. Heteroge-
neity of the effects of contrast media on mediator release. J Al-
REFERÊNCIAS lergy Clin Immunol 1996;97:838 -50.
15. Genovese A, Stellato C, Marsella CV, Adt M, Marone G. Role of
1. Singh J, Daftary A. Iodinated contrast media and their adverse mast cells, basophils and their mediators in adverse reactions to
reactions. J Nucl Med Technol 2008;36:69 -74. general anesthetics and radiocontrast media. Int Arch Allergy
2. Kvedariene V, Martins P, Rouanet L, Demoly P. Diagnosis of iodina- Immunol 1996;110:13 -22.
ted contrast media hypersensitivity: Results of a 6 -year period. 16. Ring J, Arroyave CM, Frizler MJ, Tan EM. In vitro histamine and
Clin Exp Allergy 2006;36:1072 -7 serotonin release by radiographic contrast media (RCM).
3. Dewachter P, Tréchot P, Mouton -Faivre C. “Iodine allergy”: point Complement -dependent and -independent release reaction and
of view. Ann Fr Anesth Reanim 2005;24:40 -52. changes in ultrastructure of human blood cells. Clin Exp Immunol
4. Brockow K, Christiansen C, Kanny G, Clément O, Barbaud A, 1978;32:105 -18.
Bircher A, et al. ENDA; EAACI interest group on drug hypersen- 17. Kolb WP, Lang JH, Lasser EC. Nonimmunologic complement
sitivity. Management of hypersensitivity reactions to iodinated activation in normal human serum induced by radiographic con-
contrast media. Allergy 2005;60:150 -8. trast media. J Immunol 1978;121:1232 -8.
th
5. Ellis J, et al. ACR manual on contrast media. Version 10 Ed. USA: 18. Till G, Rother U, Gemsa D. Activation of complement by radio-
American College of Radiology; 2015. graphic contrast media: generation of chemotactic and anaphyla-
6. Shehadi WH. Adverse reactions to intravascularly administered toxin activities. Int Arch Allergy Appl Immunol 1978;56:543 -50.
contrast media. A comprehensive study based on a prospective 19. Heideman M, Jacobsson B, Lindholm N. Activation of the comple-
survey. Am J Roentgenol Radium Ther Nucl Med 1975;124:145 -52. ment system by water -soluble contrast media. A preliminary
7. Webb JA, Stacul F, Thomsen HS, Morcos SK; Members of the report. Acta Radiol Diagn (Stockh) 1976;17:733 -6.
contrast media safety committee of the European Society of 20. Kanny G, Pichler W, Morisset M, Franck P, Marie B, Kohler C, et
Urogenital Radiology. Late adverse reactions to intravascular al. T cell -mediated reactions to iodinated contrast media: evalu-
iodinated contrast media. Eur Radiol 2003;13:181 -4. ation by skin and lymphocyte activation tests. J Allergy Clin Im-
8. Liccardi G, Lobefalo G, Di Florio E, Di Iorio C, Occhiochiuso munol 2005;115:179 -85.
L, Romano L, et al. Cardarelli Hospital Radiocontrast Media and 21. Brockow K. Immediate and delayed cutaneous reactions to ra-
Anesthetic -Induced Anaphylaxis Prevention Working Group. diocontrast media. Chem Immunol Allergy 2012;97:180 -90.
Strategies for the prevention of asthmatic, anaphylactic and 22. Witten DM, Hirsch FD, Hartman GW. Acute reactions to uro-
anaphylactoid reactions during the administration of anesthet- graphic contrast medium: incidence, clinical characteristics and
ics and/or contrast media. J Investig Allergol Clin Immunol relationship to history of hypersensitivity states. Am J Roent-
2008;18:1 -11. genol Radium Ther Nucl Med 1973;119:832 -40.
19
REVIST A POR TUGUESA DE IMUNO ALERGOLOGIA