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rev port estomatol med dent cir maxilofac . 2020;61(3):97-105          103


              This study was designed following the recommendations   form a stronger area at the adhesive interface to both enamel
           of the ADA. These indicate that each group should have at least   and dentin, as both contain hydroxyapatite. 45-47  Results ob-
           30 restorations, with a minimum of 25 patients in the initial   tained with the ER technique can be explained by the incom-
           phase of the study and 20 patients after six months, as well as   plete infiltration of the deeply demineralized collagen network
           a gender and age balance between study groups. In this study,   by the bonding resin, which occurs because the phosphoric
           a universal adhesive’s clinical performance was evaluated at   acid can decalcify dentin more deeply than the adhesive can
           baseline and after 6 months. One hundred seventeen NCCLs   infiltrate. 48,49  Due to this incomplete impregnation of the de-
           were restored in 26 patients, with the adhesive applied in SE   mineralized substrate, the adhesive interface is not imperme-
           and ER modes, combined with a resin composite. Each patient   able, and, as a result, water and dentinal fluid can easily move
           received at least two cervical restorations to ensure that they   through the adhesive interface with consequent nanoinfiltra-
           had a restoration from each technique, to control various en-  tion. 50-52
           vironmental factors (such as oral hygiene, saliva composition,   Marginal discoloration was observed with both techniques,
           and diet). 33                                       but no statistically significant differences were found. In the
              Due to the expulsive configuration of the NCCLs, the reten-  ADH -ER group, one restoration exhibited deep marginal stain-
           tion of restorations depends on a strong and stable bond of   ing and another presented moderate marginal staining; these
           restorative material to dentin. The occurrence of structural   were not esthetically unacceptable. Discolorations were ob-
           changes in enamel and dentin resulting from age, such as den-  served in the gingival margins, where cementum or dentin are
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           tin sclerosis, may negatively impact the quality of that bond   more likely found than enamel margins.  In the SE technique,
           and, consequently, the retention and longevity of cervical res-  two restorations showed deep marginal staining, one resto-
           torations.  This is of special concern with NCCLs where den-  ration exhibited pronounced marginal staining, and one res-
                   34
           tin is often sclerotic and, thus, more mineralized than normal   toration presented moderate marginal staining; these were not
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           dentin. 35,36  In fact, Mjor  attributed the rather poor success   esthetically unacceptable. The discoloration was located at the
           scored with adhesives in clinical trials (in contrast to labora-  enamel margin, which may suggest the importance of includ-
           tory results) to the extreme variety of dentin composition and   ing enamel’s selective conditioning with phosphoric acid to
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           structure found clinically. 37,38                   obtain the best marginal seal of restorations.  ADH is consid-
              Reactive sclerosis occurs in response to slowly progressive   ered a mild SE adhesive, as other available universal adhesives,
           or mild irritations like mechanical or chemical erosion and   because it presents a pH of 2.5. Due to their moderately high
           abrasion in response to severe insults, like aggressive operative   pH, these adhesives have limited interaction with enamel as
           procedures, attrition, and caries. 37,39  Several studies show that   they cannot condition enamel as effectively as in the ER tech-
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           dentin sclerosis increases with age, 37,39,40  which may explain   nique, resulting in increased marginal changes.  In fact, some
           why greater restoration losses have been found in older pa-  studies concluded that additional etching of the enamel cav-
           tients: patients aged 21 -40, 41 -60, and 61 -80 years had resto-  ity margins resulted in an improved marginal adaptation on
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           ration losses of 31%, 62%, and 75%, respectively.  However,   the enamel side. However, this was not critical and did not
           other studies have shown that retention failures cannot be   affect the overall clinical success of restorations. 55,56
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           associated with substrate type only,  confirming that the pro-  Marginal discoloration may be a clinical sign of future res-
           cess of adhesion involves multifactorial aspects. Indeed, a   toration failure, but it does not imply the imminent need for
                          42
           clinical study (2000)  had an equal number of restoration fail-  replacement because these discolorations, if superficial, can
           ures in sclerotic and non -sclerotic lesions, indicating that the   be removed by polishing and routine finishing. 10,57,58
           negative interaction between dentin sclerosis and the clinical   In this study, no restoration had secondary caries, maybe
           retention of adhesive systems is yet to be confirmed. In this   because the participants selected for this study had good oral
           study, there was no relationship between age and restoration   hygiene habits. 57
           loss.                                                 In this study, there was a significant difference in postop-
              A period of 6 months to 1 year seems to be sufficient to   erative sensitivity between the SE and ER techniques at base-
           predict an adhesive’s clinical behavior accurately.  In fact, in   line. Postoperative sensitivity was higher with the ER tech-
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           this study, the 6 -month evaluation period was sufficient to   nique, possibly because phosphoric acid removes the
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           detect significant differences in the performance of the tested   peritubular dentin and fully opens the dentin tubules,  which
           adhesive system, which belongs to a novel family of universal   the adhesive may not be able to seal completely afterward. In
           adhesives for which there are insufficient clinical studies.  contrast, with the SE technique, the dentin surface is smear-
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              In this study, after 6 months, nine restorations failed as a   -layer sealed, and there is a lesser tubule opening.  Neverthe-
           result of debonding, which highlights the poor bonding effica-  less, there was no difference in postoperative sensitivity be-
           cy of ADH when used with the ER strategy. Furthermore, at 6   tween the ER and SE modes, which may be explained by the
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           months, the ER technique had poorer results than the SE tech-  pulp’s capacity to recover in cases of reversible pulpitis.  Re-
           nique for marginal adaptation (78.4% vs. 98.3%). The good per-  sults from the literature indicate that a decrease or absence of
           formance of the SE restorations is likely due to the presence   hypersensitivity may occur over time in those with NCCL res-
           of an acidic functional monomer, 10 -MDP, because calcium   torations. 57,62,63
           ions (released upon the partial dissolution of hydroxyapatite)   Regarding the effect of clinical co -variables (degree of scle-
           diffuse within the hybrid layer and assemble the MDP mole-  rosis, patient age, tooth type, and gender), no correlation was
           cules into nanolayers.  This chemical interaction between   found between these co -variables and the results presented in
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           hydroxyapatite and MDP creates a stable nanolayer, which can   the two groups at the 6 -month evaluation.
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