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           alternative treatment techniques. In the case presented, after   Revascularization for the Regeneration of Immature
           6 years of follow-up, the patient remained asymptomatic, with   Permanent Teeth: A Meta-Analysis of Clinical Efficacy. Front
           a radiopaque image suggestive of mineralized barrier forma-  Bioeng Biotechnol. 2018;6:139.
           tion, slight increase of dentinal wall thickness, and mild root   3. Orduña JFG, García MG, Dominguez P, Bucheli JC, Biedma BM,
                                                                 Sans FA, et al. Successful pulp revascularization of an
           elongation, and no radiographic signs of periapical disease.
                                                                 autotransplantated mature premolar with fragile fracture
                                                                 apicoectomy and plasma rich in growth factors: a 3-year
                                                                 follow-up. Int Endod J. 2020;53:421-33.
           Conflict of interest                                 4. Gaviño-Orduña JF, Fernández-Guallart I, Caviedes-Bucheli J,
                                                                 Espadas-Garcia M, López-López J. Regenerative endodontic
           The authors have no conflicts of interest to declare.  procedure combined with apical surgery of a necrotic
                                                                 permanent incisor with extensive periapical lesion using
                                                                 plasma rich in growth factors (PRGF): A Case report with 6
                                                                 years post-op evaluation using CBCT. J Clin Exp Dent.
           Ethical disclosures                                   2021;13:e620-5.
                                                                5. Ramezani M, Sanaei-Rad P, Hajihassani N. Revascularization
           Protection of human and animal subjects. The  authors   and vital pulp therapy in immature molars with necrotic
           declare that the procedures followed were in accordance with   pulp and irreversible pulpitis: A case report with two-year
           the regulations of the relevant clinical research ethics com-  follow-up. Clin Case Rep. 2020;8:206-10.
           mittee and with those of the Code of Ethics of the World Med-  6. Lovelace TW, Henry MA, Hargreaves KM, Diogenes A.
                                                                 Evaluation of the delivery of mesenchymal stem cells into
           ical Association (Declaration of Helsinki).           the root canal space of necrotic immature teeth after clinical
                                                                 regenerative endodontic procedure. J Endod. 2011;37:133-8.
           Confidentiality of data. The authors declare that they have   7. Kim SG. Infection and Pulp Regeneration. Dent J (Basel).
           followed their work center protocols on access to patient data   2016;4:4.
           and for its publication.                             8. Torabinejad M, Nosrat A, Verma P, Udochukwu O.
                                                                 Regenerative Endodontic Treatment or Mineral Trioxide
                                                                 Aggregate Apical Plug in Teeth with Necrotic Pulps and Open
           Right to privacy and informed consent. The authors have   Apices: A Systematic Review and Meta-analysis. J Endod.
           obtained the written informed consent of the patients or sub-  2017;43:1806-20.
           jects mentioned in the article. The corresponding author is in   9. Sponchiado-Júnior EC, Vieira WA, Frozoni M, Herkrath FJ,
           possession of this document.                          de-Jesus-Soares A. CONSORT Compliance in Randomized
                                                                 Clinical Trials of Regenerative Endodontic Treatments of
                                                                 Necrotic Immature Teeth: A Scoping Review. J Endod.
                                                                 2021;47:1751-66.
           CRediT authorship contribution statement            10. Chen MYH, Chen KL, Chen CA, Tayebaty F, Rosenberg PA, Lin
                                                                 LM. Responses of immature permanent teeth with infected
           Ary Alves Mesquita-Júnior: Conceptualization, Investigation,   necrotic pulp tissue and apical periodontitis/abscess to
           Methodology, Writing – original draft. Ingrid Luiza Mendonça   revascularization procedures. Int Endod J. 2012;45:294-305.
           Cunha: Conceptualization, Methodology, Writing – original   11. Alfahadi HR, Al-Nazhan S, Alkazman FH, Al-Maflehi N,
           draft. Norbi Rodrigues Correia: Conceptualization, Methodol-  Al-Nazhan N. Clinical and radiographic outcomes of
           ogy, Writing – review & editing. Aida Renée Assayag Hanan:   regenerative endodontic treatment performed by endodontic
                                                                 postgraduate students: a retrospective study. Restor Dent
           Conceptualization, Methodology, Writing – review & editing.   Endod. 2022;47:e24.
           Emílio Carlos Sponchiado Júnior: Conceptualization, Method-  12. Lin LM, Kahler B. A review of regenerative endodontics:
           ology, Project administration, Supervision, Writing – review &   current protocols and future directions. J Istanb Univ Fac
           editing.                                              Dent. 2017;51(3 Suppl 1):S41-51.
                                                               13. Gagnier JJ, Kienle G, Altman DG, Moher D, Sox H, Riley D, et al.
                                                                 The CARE Guidelines: Consensus-based Clinical Case
                                                                 Reporting Guideline Development. Glob Adv Health Med.
           orcid                                                 2013;2:38-43.
                                                               14. Ørstavik D, Kerekes K, Eriksen HM. The periapical index: A
           Ary Alves Mesquita-Júnior    0009-0001-8444-4850      scoring system for radiographic assessment of apical
                                                                 periodontitis. Endod Dent Traumatol. 1986;2:20-34.
           Ingrid Luiza Mendonça Cunha    0000-0002-9222-6095
                                                               15. Asgary S, Shamszadeh S, Nosrat A, Aminoshariae A, Sabeti M.
           Norbi Rodrigues Correia    0009-0007-4355-6657        Management Strategies for Immature Teeth with Pulp
           Aida Renée Assayag Hanan    0000-0001-6430-1791       Necrosis: An Umbrella Review of Systematic Reviews. Iran
           Emílio Carlos Sponchiado Júnior    0000-0001-7677-7682  Endod J. 2024;19:242-53.
                                                               16. Banchs F, Trope M. Revascularization of immature permanent
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                                                                 Endod. 2004;30:196-200.
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