Page 18 - SPEMD_61-2
P. 18

56                      rev port estomatol med dent cir maxilofac. 2020;61(2):52-56


             Although cross -sectional studies with retrospective anal-  ‘keratocystic odontogenic tumour’ for the solid variant of
           ysis represent important study methods for collecting clinical   odontogenic keratocyst? J Cranio Maxill Surg. 2018;46:942 -6.
           data, they present some limitations. The main limitation of   4. Jaeger F, Noronha MS, Silva MLV, Figueiredo MBA, Carmago
           this study is the inadequate completion of some clinical re-  SM, Campolina GM, et al. Prevalence profile of odontogenic
                                                                 cysts and tumors on Brazilian sample after the
           cords that accompanied the specimens sent for histopatho-  reclassification of odontogenic keratocyst. J Cranio Maxill
           logical examination, consequently omitting relevant informa-  Surg. 2017;45:267 -70.
           tion and impairing the observation of clinical data related to   5. Barnes L, Eveson JW, Reichart P, SIdransky D. World Health
           the studied lesions.                                  Organization Classification of Tumours. Pathology and
                                                                 genetics of head and neck tumours. 3th ed IARC Press: Lyon.
                                                                 2005. p.283 -327.
           Conclusions                                         6. El -Naggar AK, Chan JKC, Grandis JR, Takata T, Slootweg PJ.
                                                                 World Health Organization classification of tumours.
                                                                 Pathology and genetics of head and neck tumours. 3th ed
           In conclusion, the clinical and radiographic profile of recurrent   IARC Press. 2017. p. 80 -83.
           and non -recurrent OKCs observed in this study agree with   7. Azevedo RS, Cabral MG, dos Santos TC, de Oliveira AV, de
           findings commonly reported in the literature, except for the   Almeida OP, Pires FR. Histopathological features of
           lack of gender predilection. Regarding clinical characteristics,   keratocystic odontogenic tumor: a descriptive study of 177
           no gender predilection for isolated or recurrent OKCs was ob-  cases from a Brazilian population. Int J Surg Pathol.
                                                                 2012;20:154 -60.
           served. The lesions occurred mainly in adults, and the most   8. Florindo JB, Bruno OM, Landini G. Morphological
           common anatomical site was the posterior mandible, present-  classification of odontogenic keratocysts using Bouligand-
           ing mainly as a unilocular radiolucency lesion in both groups.   -Minkowski fractal descriptors. Comput Biol Med. 2017;81:1-
           In addition, OKC displayed a 13.2% recurrence rate when con-  -10.
           servatively treated by decompression and surgical enucleation.  9. Chrcanovic BR, Gomez RS. Recurrence probability for
                                                                 keratocystic odontogenic tumors: An analysis of 6427 cases. J
                                                                 Craniomaxillofac Surg. 2017;45:244 -51.
                                                              10. Fidele NB, Zhao Y, Tianfu W, Sun Y, Man Q, Liu B. Treatment of
           Acknowledgements
                                                                 Multiple Odontogenic Keratocysts Involving Chinese Patients.
                                                                 J Oral Maxillofac Surg. 2019;77:2044 -54.
           We would like to thank the Coordination for the Improve-  11. Oh JS, You JS, Kim SG. Clinical and histomorphometric
           ment of Higher Education Personnel for the scholarship   evaluation of decompression followed by enucleation in the
           (CAPES).                                              treatment of odontogenic keratocyst. J Dent Sci. 2018;13:329-
                                                                 -33.
                                                              12. Ribeiro -Júnior O, Borba AM, Alves CAF, Gouveia MM, Deboni
                                                                 MCZ, Naclério -Homem MG. Reclassification and treatment of
           Ethical disclosures                                   odontogenic keratocysts: A cohort study. Braz Oral Res.
                                                                 2017;31:e98.
           Protection of human and animal subjects. The  authors   13. Baik WK, Baik HS, Choi SH. Comprehensive orthodontic
           declare that no experiments were performed on humans or   treatment of a young girl with an odontogenic keratocyst
           animals for this study.                               and impacted teeth in the mandible. Korean J Orthod.
                                                                 2020;50:63 -71.
           Confidentiality of data. The authors declare that no patient   14. Sigua -Rodriguez EA, Goulart DR, Sverzut A, Aspirino L,
                                                                 Moraes M. Is Surgical Treatment Based on a 1 -Step or 2 -Step
           data appear in this article.                          Protocol Effective in Managing the Odontogenic Keratocyst? J
                                                                 Oral Maxillofac Surg. 2019;77:1210.e1 -1210.e7.
           Right to privacy and informed consent. The authors declare   15. Cunha JF, Gomes CC, de Mesquita RA, Andrade Goulart EM,
           that no patient data appear in this article.          de Castro WH, Gomez RS. Clinicopathologic features
                                                                 associated with recurrence of the odontogenic keratocyst: a
                                                                 cohort retrospective analysis. Oral Surg Oral Med Oral Pathol
                                                                 Oral Radiol. 2016;121:629 -35.
           Conflict of interest
                                                              16. Karaca C, Dere KA, Er N, Aktas A, Tosun E, Koseoglu OT,
                                                                 Usubutun A. Recurrence rate of odontogenic keratocyst
           The authors have no conflicts of interest to declare.  treated by enucleation and peripheral ostectomy:
                                                                 Retrospective case series with up to 12 years of follow -up.
                                                                 Med Oral Patol Oral Cir Bucal. 2018;23:443 -8.
           references                                         17. Kinard B, Hansen G, Newman M. How well do we manage the
                                                                 odontogenic keratocyst? A multicenter study. Oral Surg Oral
            1. Chandrashekar C, Patel P, Thennavan A, Radhakrishnan R.   Med Oral Pathol Oral Radiol. 2019;127:282 -8.
             Odontogenic keratocyst: Analysis of recurrence by AgNOR,   18. Gomes CC, Guimarães LM, Diniz MG, Gomez RS. Molecular
             p53 and MDM2 profiling. J Oral Maxillofac Pathol. 2020;   alterations in odontogenic keratocysts as potential
             24:184 -5.                                          therapeutic targets. J Oral Pathol Med. 2017;46:877 -82.
            2. Soluk -Tekkeşin M, Wright JM. The World Health Organization   19. Souza LB, Gordón -Núñez MA, Nonaka CF, de Medeiros MC,
             Classification of Odontogenic Lesions: A Summary of the   Torres TF, Emiliano GB. Odontogenic cysts: demographic
             Changes of the 2017 (4th) Edition. Turk Patoloji Derg.   profile in a Brazilian population over a 38 -year period. Med
             2018;34:1–18.                                       Oral Patol Oral Cir Bucal. 2010;15:583 -90.
            3. Devrim K, Omer G, Bulent C. A series of 240 odontogenic   20. Bilodeau EA, Collins BM. Odontogenic Cysts and Neoplasms.
             keratocysts: Should we continue to use the terminology of   Surg Pathol Clin. 2017;10:177 -222.
   13   14   15   16   17   18   19   20   21   22   23