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Revista Portuguesa de Estomatologia,
                                                      Medicina Dentária e Cirurgia Maxilofacial


                                                        rev port estomatol med dent cir maxilofac. 2019;60(3):104-110





           Original research

           Microhardness and flexural strength after chemical
           aging of chlorhexidine delivery systems based

           on acrylic resin



                                                                              b
                                                       b,
           Cristina Bettencourt Neves , Joana Costa *, Luís Nepomuceno , Ana Madeira ,
                                        a
                                                                                               b
                           a
           Jaime Portugal , Ana Bettencourt    c
           a  Oral and Biomedical Sciences Research Unit (UICOB), Faculdade de Medicina Dentária, Universidade de Lisboa, Lisbon, Portugal
           b  Faculdade de Medicina Dentária, Universidade de Lisboa, Lisbon, Portugal
           c  Research Institute for Medicines (iMed.ULisboa), Faculdade de Farmácia, Universidade de Lisboa, Lisbon, Portugal



           a r t i c l e   i n f o          a b s t r a c t

           Article history:                 Objectives: To evaluate the effect of chlorhexidine incorporation on the microhardness and
           Received 9 August 2019           flexural strength of three reline acrylic resins, after a 28-day chemical aging process.
           Accepted 30 September 2019       Methods: Forty-eight specimens were fabricated according to the several possible combinations
           Available online 22 October 2019  of acrylic reline resin and concentrations of incorporated chlorhexidine (Kooliner – 0% vs. 2.5%;
                                            Ufi Gel Hard – 0% vs. 5%; and Probase Cold – 0% vs. 5%), to set 6 experimental groups (n=8).
           Keywords:                        After a 4-week chemical aging process (pH fluctuation in artificial saliva, with cycles of 6 hours
           Acrylic resins                   at pH=3 and 18 hours at pH=7), the Knoop microhardness (98.12 mN, 30 seconds) and flexural
           Chlorhexidine                    strength (1 kN, 5 mm/min) of all specimens were evaluated. Data were submitted to non-par-
           Denture relining                 ametric statistical tests, according to Kruskal-Wallis and Mann-Whitney (α=0.05).
           Denture stomatitis               Results: Chlorhexidine incorporation did not significantly affect the microhardness of the
           Hardness                         three tested resins (Kooliner – p=0.798; Ufi Gel Hard – p=0.798; and Probase Cold – p=0.195).
           Flexural strength                Although chlorhexidine incorporation did not influence the flexural strength of Kooliner
                                            (p=0.959) and Ufi Gel Hard (p=0.645), the incorporation of 5% chlorhexidine in Probase Cold led
                                            to a statistically lower flexural strength than that obtained without incorporation (p=0.021).
                                            Conclusion: After chemical aging, the microhardness of chlorhexidine-incorporated acrylic res-
                                            ins is not affected. However, the incorporation of 5% chlorhexidine into Probase Cold negative-
                                            ly affects its flexural strength.  (Rev Port Estomatol Med Dent Cir Maxilofac. 2019;60(3):104-110)
                                                            © 2019 Sociedade Portuguesa de Estomatologia e Medicina Dentária.
                                                 Published by SPEMD. This is an open access article under the CC BY-NC-ND license
                                                                       (http://creativecommons.org/licenses/by-nc-nd/4.0/).









             *  Corresponding author.
            E-mail address: cristina.neves@fmd.ulisboa.pt (Cristina Bettencourt Neves).
           http://doi.org/10.24873/j.rpemd.2019.10.458
           1646-2890/© 2019 Sociedade Portuguesa de Estomatologia e Medicina Dentária. Published by SPEMD.
           This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
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