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rev port estomatol med dent cir maxilofac . 2021;62(1):42-49             47
                 Figure 8. Timeline of interventions and outcomes. Oral health approach in Coffin-Siris Syndrome.


                                                     2018                        Clinical diagnosis -CSS

                  Genetic counseling and Multidisciplinary Care

                 Cardiologist, Otorhinolaryngologist ,Speech                      Emergency appointment
                 therapist and Dentistry.                                       "spontaneous pain in a posterior
                                                                                           tooth"

                                                 March, 2019                        Intraoral examination
                             Anamnesis and                                                Gingivitis
                           physical examination                                      Gingival hyperplasia
                         (Syndrome identification)                                 Enamel hypomineralization
                                                                                        Caries lesions
                 Treatment planning:
                 Dental prophylaxis
                 Instructions on Oral hygiene
                 Extraction                                                        Permanent tooth extraction
                 Restoration


                                                                  + 7 days
                                                                                      Firs appointment:
                                                                                      Suture was removed
                                                                                      Dental prophylaxis
                                                                                 Instructions on Oral hygiene and
                                                                                        dietary advice
                                                                                     Behavior Management

                                                                  + 7 days

                                                                                     Second appointment:
                                                                                         Restoration


                      Follow-up 14 days
                    The oral condition was
                           improved                                    + 14 days







                      Follow-up every 3
                           months
                    The oral condition was
                           improved               March 2020



            Figure 8. Timeline of interventions and outcomes. Oral health approach in Coffin -Siris Syndrome.


           recognized to be multifactorial and caused by gingival fibro-  phylactic periodontal therapy associated with oral hygiene
           blast dysfunction.                                  instructions can be used to treat gingival hyperplasia. In the
              Gingival hyperplasia or hypertrophy makes it difficult to   present case, after professional prophylaxis and guidance on
           maintain oral hygiene and, often, masticatory function, lead-  oral hygiene habits, the clinical condition improved in 2
                                           20
           ing to bacterial biofilm accumulation.  Conservative pro-  weeks. Patients with gingival hyperplasia should be careful-
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